SFA Overview

KBase/SFA Collaborations

The Department of Energy (DOE) funds different Science Focus Areas (SFAs) among the national laboratories to further science, pool each laboratory’s strengths, and encourage collaborations. The research efforts of these SFAs support the goals and mission of the Office of Biological and Environmental Research (BER).  Currently, KBase has ongoing collaborations with five of these SFAs. The combined research efforts of these collaborations span more than 90 people across 7 national laboratories, 17 universities, and 2 DOE User Facilities. See summaries of each of the SFAs below, and follow the links to learn more.


Bacterial-Fungal Interactions SFA

Bacterial-fungal interactions within the soil are the focus of this SFA, located at Los Alamos National Laboratory (LANL). Learn more.


The ENIGMA SFA is located at Lawrence Berkeley National Laboratory (LBNL) and strives to understand the relationship between molecules, microbes, communities, and the ecosystems they inhabit. Learn more.

Biofuels & Bioenergy SFA

The first of two SFAs located at Lawrence Livermore National Laboratory (LLNL), the Biofuels SFA is focused on the community systems biology of microbial consortia that are closely associated with bioenergy-relevant plants and algae.  Learn more.

Soil Microbiome SFA

Also located at LLNL, the Soil Microbiome SFA studies soil metagenomes to uncover the mechanisms of the critical role that microbes play in the carbon cycle within the soil. Learn more.

Biofuels & Protein Structure SFA

Studying lignocellulosic biomass and how it can be used to generate renewable biofuels is the focus of this SFA, located at Oak Ridge National Laboratory (ORNL).  Learn more.


Developmental Support

Our SFA collaborations benefit KBase users and SFAs alike through the development and implementation of new and exciting tools. To make the process of adding the SFA’s tools to KBase flow smoothly, each collaboration begins with a week-long in-person software development kit (SDK) training session. This is followed by continual developmental support to ensure SFAs are able to build, test, and deploy Apps on the KBase platform. All Apps are open source and available to everyone with a free KBase account. More information on our SDK can be found here.