Create a subset of gene expression values including only genes, which match genes provided in a list.
This App lets users select a subset of expression values from an ExpressionMatrix which corresponds to a set of genes of interest.
It takes two inputs: (i) an ExpressionMatrix object (a table of transcript expression values, where rows correspond to genes and columns correspond to experiment conditions, such as that produced from the StringTie or Cufflinks Apps; and (ii) a genome FeatureSet, such as that produced by Build FeatureSet from Genome or one of the BLAST or HMMER search Apps.
This App produces a new, smaller ExpressionMatrix object (its name formed from the input matrix and the input suffix), which has only those rows corresponding to the genes in the input feature set.
Team members who developed & deployed algorithm in KBase: James Jeffryes. For questions, please contact us.
Related Publications
- Arkin AP, Cottingham RW, Henry CS, Harris NL, Stevens RL, Maslov S, et al. KBase: The United States Department of Energy Systems Biology Knowledgebase. Nature Biotechnology. 2018;36: 566. doi: 10.1038/nbt.4163 , https://www.nature.com/articles/nbt.4163
App Specification:
https://github.com/kbaseapps/FeatureSetUtils/tree/e31f1e7de3ce34a595574e7edfa2a85944cd07a0/ui/narrative/methods/filter_matrix_by_feature_setModule Commit: e31f1e7de3ce34a595574e7edfa2a85944cd07a0