Trim a Multiple Sequence Alignment (MSA) to remove hypervariable (gappy) regions with Gblocks
Gblocks 0.91b from http://molevol.cmima.csic.es/castresana/Gblocks.html
This method trims Multiple Sequence Alignments (MSAs) to capture the conserved blocks that may be more reliable regions from which to compare evolutionary rates, such as for tree building. It uses the method Gblocks.
- Castresana J. Selection of Conserved Blocks from Multiple Alignments for Their Use in Phylogenetic Analysis. Mol Biol Evol. 2000;17: 540 552. doi:10.1093/oxfordjournals.molbev.a026334 , https://academic.oup.com/mbe/article/17/4/540/1127654
- Talavera G, Castresana J, Kjer K, Page R, Sullivan J. Improvement of Phylogenies after Removing Divergent and Ambiguously Aligned Blocks from Protein Sequence Alignments. Syst Biol. 2007;56: 564 577. doi:10.1080/10635150701472164 , https://academic.oup.com/sysbio/article/56/4/564/1682121
Module Commit: 2f1824e463b0fe54cb2da6766d779d8a37c14298