A collaborative, open environment for systems biology

of plants, microbes and their communities

KBase: The U.S. Department of Energy Systems Biology Knowledgebase

In KBase, you can create shareable, reproducible workflows called Narratives that include data, analysis steps, results, visualizations and commentary.

Research Highlights

Accurately predicting biosynthetic energy yields is a challenging problem. In work published in BMC Genomics, KBase scientists developed new analysis tools that allowed them to address this problem by building core metabolic models representing 48 major phylogenetic microbial groups.

In a cover article in the Journal of Cellular Physiology, KBase scientist Christopher Henry and collaborators demonstrate strategies for constructing genome-scale metabolic networks that simulate two species in a microbial consortium exchanging metabolites to sustain life.

Integrated Data and Tools

Analyze a wide range of public bioinformatics data together with your own data.


Explore KBase’s analysis tools (Apps) in the App Catalog.


Transfer high-throughput sequencing data from   the JGI Genome Portal to KBase for analysis.


KBase is an open platform — find out how to add your own analysis tools!


Latest News

Video Tutorials: Data in KBase

New video tutorials that explain how to find, upload and manage data in KBase are now available on our YouTube channel: https://www.youtube.com/channel/UCTX9Pn_WCCCpOER9-3AGL_A. The first short video discusses how to search for data that’s already in KBase and add it to your Narrative for analysis, as well as how to upload data from your computer. The second […]

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