Create an average ExpressionMatrix data object with one column per condition.
This App takes as input an ExpressionMatrix object and creates an output ExpressionMatrix object consisting of one column per condition averaged over all the replicates for the given condition. The output matrix, therefore, has the same number of columns as there are conditions.
NOTE: The average value for a given feature row and a condition column is computed by taking the arithmetic average of the replicate columns associated with the condition and the feature.
Team members who developed & deployed algorithm in KBase: Tianhao Gu. For questions, please contact us.
Related Publications
- Arkin AP, Cottingham RW, Henry CS, Harris NL, Stevens RL, Maslov S, et al. KBase: The United States Department of Energy Systems Biology Knowledgebase. Nature Biotechnology. 2018;36: 566. doi: 10.1038/nbt.4163 , https://www.nature.com/articles/nbt.4163
App Specification:
https://github.com/kbaseapps/FeatureSetUtils/tree/e31f1e7de3ce34a595574e7edfa2a85944cd07a0/ui/narrative/methods/compute_average_expression_matrixModule Commit: e31f1e7de3ce34a595574e7edfa2a85944cd07a0